[Anti-herpes chemotherapy].

With the increasing number of immunocompromised patients over the last two decades, disease pattern caused by Herpesviridae has changed. More virulent, more severe, herpesvirus diseases are more frequently treated and consequently the drug-resistant herpesvirus mutants have arisen in the clinic. All these events justify to explore future directions in drug development and herpesviral research as antisens strategy or immunotherapy.