Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials · 2011
[Simulation study of antithrombotic active fraction of Naodesheng by support vector machine].
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Li Shu-xian, Chen Chao, Wang Shu-mei, Deng Xiao-hui, Liang Sheng-wang
Аннотация
OBJECTIVE: To screen the antithrombotic active fraction of Naodesheng.
METHODS: The collagen and adrenaline-induced thrombosis by tail intravenous injection in mice was used. Based on orthogonal design, the support vector machine model was established for pharmacodynamics prediction of TCM prescriptions.
RESULTS: The model established in this study could predict the drug actions of different combinations.
CONCLUSION: The pharmacodynamic actions of several formulas are superior to that of the original formula and CD has the best effect.
METHODS: The collagen and adrenaline-induced thrombosis by tail intravenous injection in mice was used. Based on orthogonal design, the support vector machine model was established for pharmacodynamics prediction of TCM prescriptions.
RESULTS: The model established in this study could predict the drug actions of different combinations.
CONCLUSION: The pharmacodynamic actions of several formulas are superior to that of the original formula and CD has the best effect.