Медицинская библиотека · Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials · 2011

[Simulation study of antithrombotic active fraction of Naodesheng by support vector machine].

Li Shu-xian, Chen Chao, Wang Shu-mei, Deng Xiao-hui, Liang Sheng-wang

Аннотация на английскомСтатьяПеревод в очереди

Аннотация

OBJECTIVE

To screen the antithrombotic active fraction of Naodesheng.

METHODS

The collagen and adrenaline-induced thrombosis by tail intravenous injection in mice was used. Based on orthogonal design, the support vector machine model was established for pharmacodynamics prediction of TCM prescriptions.

RESULTS

The model established in this study could predict the drug actions of different combinations.

CONCLUSION

The pharmacodynamic actions of several formulas are superior to that of the original formula and CD has the best effect.

Для цитирования: Li Shu-xian, Chen Chao, Wang Shu-mei, Deng Xiao-hui, Liang Sheng-wang. [Simulation study of antithrombotic active fraction of Naodesheng by support vector machine].. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2011.

Предметные рубрики MeSH

Algorithms Animals Chemical Fractionation Computer Simulation Drug Combinations Drug Discovery Drugs, Chinese Herbal Female Fibrinolytic Agents Male Mice Mice, Inbred Strains Models, Statistical Plants, Medicinal Random Allocation Structure-Activity Relationship Support Vector Machine Thrombosis

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