[Discrete plasmapheresis for coronary heart disease].

AIM: To provide a rationale for the expediency and efficiency of discrete plasmapheresis (PA) in the package of therapeutic measures for coronary heart disease (CHD).

SUBJECTS AND

METHODS

585 sessions or 120 cycles of low-volume therapeutic PA were performed in 91 patients with CHD. The parameters of blood lipid composition, hemocoagulation, rheology, and endotoxicosis were studied.

RESULTS

Removal of 100% circulating plasma volume per treatment cycle could achieve a significant positive result of abnormally higher homeostatic parameters. The levels of high-density lipoprotein cholesterol, antithrombin III, and albumin did not decrease significantly.

CONCLUSION

Low-volume discrete PA is a pathogenetically sound and effective method to affect homeostasis in CHD.