Anesteziologiia i reanimatologiia · 2010
[Optimization of the neuroautonomic inhibition and regulation of hemodynamics during subarachnoid anesthesia in abdominal delivery].
Аннотация на английскомСтатьяРандомизированное исследованиеНазвание и аннотация: Перевод в очереди
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Gur'ianov V A, Tolmachev G N, Volodin A V, Marichik N V, Nemirovskiĭ V B
Аннотация
Pregnancy is considered in the spotlight of creation of general adaptation syndrome. It was revealed that 85% and 58% of healthy non-pregnant women had an inadequate autonomous nervous system (ANS) and circulatory system response respectively. This favoured the labour activity malfunction in 20% of women in childbirth when an abdominal delivery was needed. A traditional subarachnoid anesthesia (SA) in control group was accompanied by decrease of blood pressure (BP) to the numbers requiring a medicamentous correction (as by literature data). However, the central haemodynamics measures has shown a normal blood flow and the blood pressure correction was not performed. During surgery and in early post-operative period in all women in this group a parasympathetic tone has prevailed over, and the cardiac output was at the lower limit of the hypokinetic type of haemodynamics, which was accompanied with nausea and vomiting in 30% of women. Including the atropine administration into the traditional protocol of SA in cesarean section in pregnant patients with eu- and parasympathotonia (research group) has favoured the optimization of the neurovegetative inhibition of reflexes and stabilization of haemodynamics within the physiological ranges. Vagosympathetic block has been accompanied by sympathotonia with a lesser BP decrease compared to control group, absence of bradycardia, nausea and vomiting. Thus the BP can not serve as a criterion of the perfusion of essential organs, including uteroplacental haemodynamics, especially non-invasibe BP. Including the control of ANS tone dynamics, central haemodynamics and oxygen transport into monitoring guidelines in neuroaxial anaesthesia in abdominal delivery is necessary.
Предметные рубрики MeSH
Adaptation, PhysiologicalAdjuvants, AnesthesiaAnesthesia, ObstetricalAnesthesia, SpinalAnesthetics, LocalApgar ScoreAtropineAutonomic Nervous SystemBupivacaineCesarean SectionFemaleHemodynamicsHumansHydroxyethyl Starch DerivativesInfant, NewbornMonitoring, IntraoperativePlasma SubstitutesPregnancySubarachnoid Space