The American journal of tropical medicine and hygiene · 2022
COVID-19 Vaccine Effectiveness during a Prison Outbreak when Omicron was the Dominant Circulating Variant-Zambia, December 2021.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Simwanza John, Hines Jonas Z, Sinyange Danny, Sinyange Nyambe, Mulenga Chilufya, Hanyinza Sarah, Sakubita Patrick, Langa Nelia, Nowa Haggai, Gardner Priscilla, Saasa Ngonda, Chitempa Graham, Simpungwe James, Malambo Warren, Hamainza Busiku, Chipimo Peter J, Kapata Nathan, Kapina Muzala, Musonda Kunda, Liwewe Mazyanga, Mwale Consity, Fwoloshi Sombo, Mulenga Lloyd B, Agolory Simon, Mukonka Victor, Chilengi Roma
Аннотация
During a COVID-19 outbreak in a prison in Zambia from December 14 to 19, 2021, a case-control study was done to measure vaccine effectiveness (VE) against infection and symptomatic infection, when the Omicron variant was the dominant circulating variant. Among 382 participants, 74.1% were fully vaccinated, and the median time since full vaccination was 54 days. There were no hospitalizations or deaths. COVID-19 VE against any SARS-CoV-2 infection was 64.8%, and VE against symptomatic SARS-CoV-2 infection was 72.9%. COVID-19 vaccination helped protect incarcerated persons against SARS-CoV-2 infection during an outbreak while Omicron was the dominant variant in Zambia. These findings provide important local evidence that might be used to increase COVID-19 vaccination in Zambia and other countries in Africa.