Bacterial shock.

Bacterial shock due to Gram-negative bacilli is best managed by prompt control of the infection with appropriate antibiotics and surgical drainage or excision. Corticosteroids for purposes of controlling systemic reactions to bacteria and their toxins constitute adjunctive therapy. Volume repletion and respiratory support may be of the greatest importance for temporary support of these critically ill patients. Vasoactive drugs including dopamine and isoproterenol should be used very sparingly and only as very temporary expedients.