Midnight medicine: Empowering night shift to treat opioid use disorder (OUD).

Hospitalizations for opioid use disorder (OUD) are rising, yet overnight clinicians rarely receive targeted OUD education. Our interprofessional initiative implemented two overnight training sessions specifically for night-shift physicians, nurses, pharmacists, and advanced practice providers, emphasizing buprenorphine initiation, stigma reduction, harm reduction, and patient-centered communication. Participants in the program demonstrated increased confidence in OUD management and a self-reported rise in overnight buprenorphine initiation, highlighting the impact of this tailored night-shift education. Administrative support enabled participation through scheduling adjustments and incentives, while collaboration with TeachOUD enriched content with community resources. To improve overnight care in resource-limited hospitals, we highlight no-cost resources, including teleconsultation hotlines, quick-reference tools, and training designated night-shift OUD champions, promoting accessible and sustainable strategies to enhance OUD care at all hours of the day.