Annals of cardiac anaesthesia · 2026
Efficacy of Ropivacaine Infiltration by Presternal Multi-orifice Catheter for Post-Sternotomy Pain Relief in Adult Patients Undergoing Cardiac Surgery-A Prospective, Randomized, Control Study.
СтатьяРандомизированное исследованиеНазвание и аннотация: Перевод в очереди
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Swetha L S Naga, Prakash Mohit, Hasija Suruchi, Gayatri B Sushama, Chauhan Sandeep, Jha Pratik K
Аннотация
BACKGROUND AND AIMS: Post-sternotomy pain management remains a key concern in adult cardiac surgery. This study evaluated the efficacy and safety of ropivacaine infiltration via a presternal multi-orifice catheter for postoperative analgesia.
DESIGN: A prospective randomized controlled trial.
SETTING: A single tertiary care center.
MATERIAL AND METHODS: A total of 175 adult patients undergoing cardiac surgery via median sternotomy were randomized into three groups: Group A (n = 58): Received 0.375% ropivacaine as continuous infusion at 5 mL/hour, Group B (n = 58): Received 5 mL of 0.375% ropivacaine as intermittent boluses every 8 hours, and Group C (n = 59): Received conventional intravenous tramadol. Pain was assessed using the visual analogue scale (VAS) for 48 hours post-extubation. Intravenous tramadol was used as rescue analgesia if VAS≥3.
RESULTS: Group B reported significantly lower VAS scores and rescue tramadol requirements (56 ± 35 mg) compared to Group A (155 ± 32 mg) and Group C (135 ± 45 mg). No significant differences were observed among the groups regarding hemodynamic parameters, catheter-related infections, time to extubation, or intensive care unit (ICU) stay.
CONCLUSION: Presternal infiltration of 0.375% ropivacaine is safe and effective for post-sternotomy analgesia. The intermittent bolus technique provides superior pain relief and reduces opioid consumption compared to continuous infusion and standard intravenous analgesia.
DESIGN: A prospective randomized controlled trial.
SETTING: A single tertiary care center.
MATERIAL AND METHODS: A total of 175 adult patients undergoing cardiac surgery via median sternotomy were randomized into three groups: Group A (n = 58): Received 0.375% ropivacaine as continuous infusion at 5 mL/hour, Group B (n = 58): Received 5 mL of 0.375% ropivacaine as intermittent boluses every 8 hours, and Group C (n = 59): Received conventional intravenous tramadol. Pain was assessed using the visual analogue scale (VAS) for 48 hours post-extubation. Intravenous tramadol was used as rescue analgesia if VAS≥3.
RESULTS: Group B reported significantly lower VAS scores and rescue tramadol requirements (56 ± 35 mg) compared to Group A (155 ± 32 mg) and Group C (135 ± 45 mg). No significant differences were observed among the groups regarding hemodynamic parameters, catheter-related infections, time to extubation, or intensive care unit (ICU) stay.
CONCLUSION: Presternal infiltration of 0.375% ropivacaine is safe and effective for post-sternotomy analgesia. The intermittent bolus technique provides superior pain relief and reduces opioid consumption compared to continuous infusion and standard intravenous analgesia.