The relationship between COVID-19 and opioid-related emergency department visits in Alberta, Canada: an interrupted time series analysis.

INTRODUCTION

Emergency departments (EDs) are important health care access points for people who use drugs (PWUD), but little is known about whether the onset of the COVID-19 pandemic was associated with changes in opioid-related emergency presentations. We investigated whether (1) the onset of the COVID-19 pandemic was associated with any change in average rates of opioid-related ED visits in Alberta; and (2) this varied across regions with different COVID-19 case rates.

METHODS

We conducted maximum-likelihood interrupted time series analyses to compare opioid-related ED visits during the "prepandemic period" (3 March 2019-1 March 2020) and the "pandemic period" (2 March 2020-14 March 2021).

RESULTS

There were 8883 and 11 657 opioid-related ED visits during the prepandemic and pandemic periods, respectively. The onset of the COVID-19 pandemic was associated with an increase in opioid-related ED visits (Edmonton: IRR = 1.37, 95% CI: 1.30- 1.44, p < 0.05; Calgary: IRR = 1.14, 95% CI: 1.07-1.20, p < 0.05; Other health zones: IRR = 1.14, 95% CI: 1.07-1.21, p < 0.05). Changing COVID-19 case counts did not correspond with changing rates of opioid-related ED visits across regions.

CONCLUSION

The increase in opioid-related ED visits associated with the onset of the COVID-19 pandemic was unrelated to COVID-19 case prevalence in Alberta.