Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
Frequency and predictors of risk of non-medical opioid use among patients with cancer in a specialized outpatient palliative care clinic.
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Torres-Tenor Juan Luis, Bruera Eduardo, Sánchez-Mañas Inés, Pérez-Manrique Teresa, Castellano-Candalija Aránzazu, Alonso-Babarro Alberto
Аннотация
PURPOSE: To assess non-medical opioid use (NMOU) risk frequency in outpatients with cancer, compare at-risk vs. non-risk patients, and evaluate the Screener and Opioid Assessment for Patients with Pain-Revised (SOAPP-R) against its shortened version (SOAPP-SF).
METHODS: /patients. This cross-sectional study was conducted in a tertiary hospital's palliative care clinic. Adult patients with advanced cancer and cancer pain using or initiating prescribed opioids were included. Patients self-completed the SOAPP-R and SOAPP-SF during consultations. Additional data were gathered from medical records.
RESULTS: A total of 47 patients completed SOAPP-R and SOAPP-SF to assess NMOU risk, with 28% (n = 13) classified as high-risk by both. High-risk patients were younger (p = 0.003), received higher opioid doses (p = 0.026), used more substances (p = 0.018), and were more frequently employed (p = 0.001). SOAPP-SF showed 0.85 specificity, 0.6 sensitivity, 0.85 negative predictive value, and 0.6 positive predictive value compared to SOAPP-R. Both tests agreed on 61.5% of high-risk and 85% of low-risk cases.
CONCLUSIONS: Among outpatients with advanced cancer, 28% had high NMOU risk, which was associated with younger age, higher opioid doses, greater substance use, and higher employment rates. SOAPP-SF retained most of the predictive power of the SOAPP-R.
METHODS: /patients. This cross-sectional study was conducted in a tertiary hospital's palliative care clinic. Adult patients with advanced cancer and cancer pain using or initiating prescribed opioids were included. Patients self-completed the SOAPP-R and SOAPP-SF during consultations. Additional data were gathered from medical records.
RESULTS: A total of 47 patients completed SOAPP-R and SOAPP-SF to assess NMOU risk, with 28% (n = 13) classified as high-risk by both. High-risk patients were younger (p = 0.003), received higher opioid doses (p = 0.026), used more substances (p = 0.018), and were more frequently employed (p = 0.001). SOAPP-SF showed 0.85 specificity, 0.6 sensitivity, 0.85 negative predictive value, and 0.6 positive predictive value compared to SOAPP-R. Both tests agreed on 61.5% of high-risk and 85% of low-risk cases.
CONCLUSIONS: Among outpatients with advanced cancer, 28% had high NMOU risk, which was associated with younger age, higher opioid doses, greater substance use, and higher employment rates. SOAPP-SF retained most of the predictive power of the SOAPP-R.