British journal of pain · 2022
A systematic review of subcutaneous versus intramuscular or intravenous routes of opioid administration on pain outcomes in cancer and post-surgical clinical populations - challenging current assumptions in palliative care practice.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Fairbairn Lorna, Schuberth Anna, Deacon Laura, Gilkes Hazel, Montgomery Victoria, Bennett Michael I, Mulvey Matthew R
Аннотация
OBJECTIVE: The objective of this review is to investigate the use of the subcutaneous route of administration of analgesics, common practice within palliative medicine.
DESIGN: Systematic review using consensus approach, direct comparison of subcutaneous route with intravenous and intramuscular routes.
RESULTS: The limited available evidence demonstrates non-inferiority of the subcutaneous route in both cancer patients and those post-surgery. Pain management is comparable to other routes. Route-related side effects are rare and systemic side effects are comparable.
CONCLUSION: Pain management is a critical role of palliative medicine. The subcutaneous route of administration offers a viable option for the delivery of parenteral analgesia within all settings, including the community. This review supports current practice, demonstrating equivalence with more invasive routes of administration.
DESIGN: Systematic review using consensus approach, direct comparison of subcutaneous route with intravenous and intramuscular routes.
RESULTS: The limited available evidence demonstrates non-inferiority of the subcutaneous route in both cancer patients and those post-surgery. Pain management is comparable to other routes. Route-related side effects are rare and systemic side effects are comparable.
CONCLUSION: Pain management is a critical role of palliative medicine. The subcutaneous route of administration offers a viable option for the delivery of parenteral analgesia within all settings, including the community. This review supports current practice, demonstrating equivalence with more invasive routes of administration.