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DOI 10.1136/spcare-2022-003964

Медицинская библиотека · BMJ supportive & palliative care · 2024

Opioids in advanced cancer: use, storage and disposal in the home.

Mercadante Sebastiano, Adamoli Lucia, Bellavia Giuseppe, Castellana Luisa, Favara Tommaso, Insalaco Lavinia, Mauceri Marco, Scibilia Carla, Lo Mauro Mario, Lo Cascio Alessio, Casuccio Alessandra

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Аннотация

OBJECTIVES

To determine the patterns of storing, using and disposing of opioids among patients with advanced cancer followed at home.

METHODS

Patients who were prescribed opioids were selected. Prescribed opioids and their doses used for background pain and breakthrough pain were collected, as well as CAGE (cut down, annoyed, guilty and eye opener) for alcohol and drugs, smoking and history of illicit substance use. Questions regarding the opioid use, storage and disposal were posed.

RESULTS

100 patients were surveyed. Fifty-one patients had unused opioids at home, 25 patients did not throw away the drugs, 40 patients saved opioids for future use and 35 patients were unaware of proper opioid disposal methods. A total of 28 patients reported unsafe use by sharing or losing their opioids; 12 patients were unaware that their opioid could be fatal when taken by others. Most patients acknowledged that pain medications could be dangerous when taken by others. Patients with a partner and who were married were more likely to keep their opioids locked (p=0.028 and p=0.025, respectively).

CONCLUSION

A large number of patients with advanced cancer followed at home do not store, use and dispose of opioids safely. Patient education programmes should be incorporated to decrease the availability of opioids at home for abuse, diversion, and accidental poisoning.

Для цитирования: Mercadante Sebastiano, Adamoli Lucia, Bellavia Giuseppe, Castellana Luisa, Favara Tommaso, Insalaco Lavinia, Mauceri Marco, Scibilia Carla, Lo Mauro Mario, Lo Cascio Alessio, Casuccio Alessandra. Opioids in advanced cancer: use, storage and disposal in the home.. BMJ supportive & palliative care. 2024. DOI: 10.1136/spcare-2022-003964.

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