Fertility and sterility · 2014
A retrospective cohort study to evaluate the impact of meaningful weight loss on fertility outcomes in an overweight population with infertility.
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Kort Jonathan D, Winget Caitlin, Kim Sun H, Lathi Ruth B
Аннотация
OBJECTIVE: To determine if meaningful weight loss (≥10%) improved conception and live birth rates of overweight patients with infertility.
DESIGN: A retrospective cohort study.
SETTING: Academic medical center.
PATIENT(S): Overweight patients (body mass index ≥25 kg/m(2); n = 52) being treated for infertility and referred for weight loss counseling.
INTERVENTION(S): Patients were given a "meaningful" weight loss goal of 10%. They were followed by an endocrinologist who provided diet and exercise recommendations, metabolic screening, and pharmacologic intervention when indicated.
MAIN OUTCOME MEASURE(S): Pregnancy rate, live birth rate, weight loss.
RESULT(S): Thirty-two percent of the patients achieved meaningful weight loss. Patients achieving meaningful weight loss had significantly higher conception (88% vs. 54%) and live birth rates (71% vs. 37%) than those who did not.
CONCLUSION(S): Weight loss improves live birth rates in overweight patients with infertility. Health care providers should incorporate weight loss counseling when caring for overweight patients who plan to conceive.
DESIGN: A retrospective cohort study.
SETTING: Academic medical center.
PATIENT(S): Overweight patients (body mass index ≥25 kg/m(2); n = 52) being treated for infertility and referred for weight loss counseling.
INTERVENTION(S): Patients were given a "meaningful" weight loss goal of 10%. They were followed by an endocrinologist who provided diet and exercise recommendations, metabolic screening, and pharmacologic intervention when indicated.
MAIN OUTCOME MEASURE(S): Pregnancy rate, live birth rate, weight loss.
RESULT(S): Thirty-two percent of the patients achieved meaningful weight loss. Patients achieving meaningful weight loss had significantly higher conception (88% vs. 54%) and live birth rates (71% vs. 37%) than those who did not.
CONCLUSION(S): Weight loss improves live birth rates in overweight patients with infertility. Health care providers should incorporate weight loss counseling when caring for overweight patients who plan to conceive.