AACE endocrinology and diabetes · 2025
Early-Onset Type 2 Diabetes in Bangladesh: National Estimates and Risk Correlates.
СтатьяНазвание и аннотация: Перевод в очереди
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Hasan Mashfiqul, Morshed Md Shahed, Tofail Tania, Sultana Nusrat, Banu Hurjahan, Rahman Mohammad Atiqur, Ferdousi Tahmina, Roy Indira, Alam Mohammad Fakhrul, Aktar Yasmin, Shil Kishore Kumar, Ratul Rifat Hossain, Salam Sayad Bin Abdus, Ashraf Koushik, Al Noman Bhuiyan Abdullah, Chowdhury Prodipta, Islam Md Hasanul, Iliyas Samirah Binte, Airi Krishna, Yasmin Hilary, Siddika Munira Afroz, Rahman Farhana, Akter Nazia, Uddin Milon Md Sarowar, Prasad Indrajit, Arafat Shohael Mahmud, Hasanat Muhammad Abul
Аннотация
OBJECTIVE: Early-onset type 2 diabetes (T2D) is an emerging public health concern. Despite its rising burden, national data on the prevalence and risk factors in Bangladesh remain scarce. This study aimed to estimate the prevalence of early-onset T2D and identify risk factors among young people in Bangladesh.
METHODS: This nationwide, population-based survey encompassed 2,300 young people-adolescents (10-18 years) and young adults (19-34 years)-from rural and urban sites across 8 divisions of Bangladesh using multistage random sampling in 2024. Glycemic status (by oral glucose tolerance test except in pre-existing diabetes mellitus), fasting lipid profile, sociodemographics, lifestyle, anthropometry, and blood pressure were assessed. Glucose was measured by the glucose-oxidase method, and lipids by the enzymatic method.
RESULTS: Prevalence of early-onset T2D and prediabetes was 4.5% (104/2,300) and 18.4% (423/2,300), respectively. Among those with diabetes, 66.3% (69/104) were newly diagnosed. Diabetes prevalence was higher in young adults (89/1,182; 7.5%) than in adolescents (15/1,118; 1.3%), and in urban residents (65/1,079; 6.0%) than in rural residents (39/1,221; 3.2%) (P < .05 for both). Higher odds for diabetes were linked with suboptimal physical activity (odds ratio [OR] 2.0, 95% CI: 1.1-4.0), smokeless tobacco use (OR 2.6, 95% CI: 1.4-4.9), central obesity (OR 2.0, 95% CI: 1.3-3.3), hypertension (OR 3.3, 95% CI: 1.6-6.7), and hypertriglyceridemia (OR 2.9, 95% CI: 1.8-4.5).
CONCLUSION: Early-onset T2D affects 4.5% of young people in Bangladesh, whereas 18.4% have prediabetes. Prevalence is higher in young adults and urban residents. Suboptimal physical activity, smokeless tobacco use, central obesity, hypertension, and hypertriglyceridemia are key risk factors.
METHODS: This nationwide, population-based survey encompassed 2,300 young people-adolescents (10-18 years) and young adults (19-34 years)-from rural and urban sites across 8 divisions of Bangladesh using multistage random sampling in 2024. Glycemic status (by oral glucose tolerance test except in pre-existing diabetes mellitus), fasting lipid profile, sociodemographics, lifestyle, anthropometry, and blood pressure were assessed. Glucose was measured by the glucose-oxidase method, and lipids by the enzymatic method.
RESULTS: Prevalence of early-onset T2D and prediabetes was 4.5% (104/2,300) and 18.4% (423/2,300), respectively. Among those with diabetes, 66.3% (69/104) were newly diagnosed. Diabetes prevalence was higher in young adults (89/1,182; 7.5%) than in adolescents (15/1,118; 1.3%), and in urban residents (65/1,079; 6.0%) than in rural residents (39/1,221; 3.2%) (P < .05 for both). Higher odds for diabetes were linked with suboptimal physical activity (odds ratio [OR] 2.0, 95% CI: 1.1-4.0), smokeless tobacco use (OR 2.6, 95% CI: 1.4-4.9), central obesity (OR 2.0, 95% CI: 1.3-3.3), hypertension (OR 3.3, 95% CI: 1.6-6.7), and hypertriglyceridemia (OR 2.9, 95% CI: 1.8-4.5).
CONCLUSION: Early-onset T2D affects 4.5% of young people in Bangladesh, whereas 18.4% have prediabetes. Prevalence is higher in young adults and urban residents. Suboptimal physical activity, smokeless tobacco use, central obesity, hypertension, and hypertriglyceridemia are key risk factors.