Forging spiro-dibenzoxazepane indano-succinimides through direct diastereoselective [3+2] annulation.

Herein, a Cp*Rh(III)-catalyzed diastereoselective direct [3+2]-spiroannulation of dibenz[b,f]oxazepines with N-substituted maleimides as C2 synthon, enables access to spiro-dibenzoxazepane indano-succinimides. This methodology features broad substrate scope, excellent functional-group tolerance, and mechanistic insight, affording products in good to excellent yields under mild conditions, enabled by the unique reactivity of the seven-membered cyclic ketimine directing group.