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DOI 10.4103/aian.aian_933_24

Медицинская библиотека · Annals of Indian Academy of Neurology · 2025

Educational and Socioeconomic Correlates of Stroke Risk Behaviors: Findings from the SPRINT INDIA Trial.

Verma Shweta Jain, Kaur Gurnoor, Devi Arya, Arora Deepti, Dhasan Aneesh, Sylaja P N, Khurana Dheeraj, Pamidimukkala Vijaya, Ray Biman Kanti, Nambiar Vivek, Aaron Sanjith, Mittal Gaurav, Nagarjunakonda Sundarachary, Pai Aparna R, Gorthi Sankar Prasad, Kumaravelu Somasundaram, Reddy Yerasu Muralidhar, Narayan Sunil, Borah Nomal Chandra, Das Rupjyoti, Kulkarni Girish Baburao, Huded Vikram, Mathew Thomas, Srivastava Mv Padma, Bhatia Rohit, Ojha Pawan Kumar, Roy Jayanta, Abraham Sherly Mary, Vaishnav Anand Girish, Sharma Arvind, Jabeen Sheikh, Pathak Abhishek, Bhoi Sanjeev Kumar, Sharma Sudhir, Sulena Sulena, Saroja Aralikatte Onkarappa, Ramrakhiani Neetu, Kempegowda Madhusudhan Byadarahalli, Kate Mahesh, George Tina, Sebastian Ivy, Sharma Meenakshi, Dhaliwal Rupinder, Huilgol Rahul, Pandian Jeyaraj D

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Аннотация

BACKGROUND AND

OBJECTIVES

Secondary Prevention by Structured Semi-Interactive Stroke Prevention Package in India (SPRINT INDIA) trial was a randomized control trial that enrolled 4298 stroke patients and administered educational interventions at 31 centers across India, with the aim to reduce recurrent stroke through increased stroke knowledge. This SPRINT INDIA trial post hoc study aims to investigate the incidence of recurrent stroke, high-risk transient ischemic attack (TIA), acute coronary syndrome (ACS), death, and lifestyle behavioral factors at 1 year. In addition, it examines the relationship between patients' baseline characteristics and education levels, risk factors, and outcomes and performs subgroup analysis within the intervention and control groups.

METHODS

Participants were randomly assigned (1:1) to either intervention or control group through computer-based randomization on web. Intervention included stroke prevention Short Message Service messages, short-duration videos, and printed workbooks. Baseline assessments captured demographic and educational data, classifying patients into three categories: no schooling, less than high school, and high school or above. Primary outcome was a composite of recurrent stroke, high-risk TIA, ACS, and mortality at 1 year. Chi-square tests and analysis of variance were used to evaluate educational disparities across various variables.

RESULTS

The intervention did not reduce primary outcomes at 1 year among patients with different educational levels. Higher educational group was associated with enhanced medication adherence (94.3% vs 85.4%; P < 0.001), increased physical activity (5497.91 ± 4117.7 vs 6169.91±4828.8; P < 0.001), lower triglyceride levels, and decreased engagement in behavioral risk factors like alcohol intake (5.1% vs 6.8%; P = 0.013) and tobacco use (smoked and chewed) (4% vs 7.9%; P < 0.001 and 5.8% vs 11.6%; P = 0.020).

CONCLUSIONS

Personalized secondary stroke prevention, tailored to educational levels, is crucial for effective stroke management.

Для цитирования: Verma Shweta Jain, Kaur Gurnoor, Devi Arya, Arora Deepti, Dhasan Aneesh, Sylaja P N, Khurana Dheeraj, Pamidimukkala Vijaya, Ray Biman Kanti, Nambiar Vivek, Aaron Sanjith, Mittal Gaurav, Nagarjunakonda Sundarachary, Pai Aparna R, Gorthi Sankar Prasad, Kumaravelu Somasundaram, Reddy Yerasu Muralidhar, Narayan Sunil, Borah Nomal Chandra, Das Rupjyoti, Kulkarni Girish Baburao, Huded Vikram, Mathew Thomas, Srivastava Mv Padma, Bhatia Rohit, Ojha Pawan Kumar, Roy Jayanta, Abraham Sherly Mary, Vaishnav Anand Girish, Sharma Arvind, Jabeen Sheikh, Pathak Abhishek, Bhoi Sanjeev Kumar, Sharma Sudhir, Sulena Sulena, Saroja Aralikatte Onkarappa, Ramrakhiani Neetu, Kempegowda Madhusudhan Byadarahalli, Kate Mahesh, George Tina, Sebastian Ivy, Sharma Meenakshi, Dhaliwal Rupinder, Huilgol Rahul, Pandian Jeyaraj D. Educational and Socioeconomic Correlates of Stroke Risk Behaviors: Findings from the SPRINT INDIA Trial.. Annals of Indian Academy of Neurology. 2025. DOI: 10.4103/aian.aian_933_24.
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