Burden and risk of elderly atopic dermatitis in Europe: A 2021 global burden of disease analysis.

BACKGROUND

The burden of atopic dermatitis (AD) in elderly is increasing recently, so it is necessary to deepen the recognition.

METHODS

We extracted prevalence, incidence and disability-adjusted life years (DALYs) for elderly-AD in Europe used Global Burden of Disease (GBD) and analyzed its related factors.

RESULTS

The burden of elderly-AD in Europe increased significantly from 1990 to 2021 (changed prevalence: 2.09%; changed DALYs: 11.58%) and females are higher than males. From the perspective of regional heterogeneity, the burden of elderly-AD in Western Europe is much heavier than other areas. Socio-demographic index (r = 0.497, P < 0.001), high alcohol use (r = 0.50, P < 0.001) and high red meat diet (r = 0.46, P < 0.001) are positively related to the incidence of elderly-AD, while low nuts and seeds intake (r = -0.50, P < 0.001), low seafood omega-3 fatty acids diet (r = -0.74, P < 0.001), low omega-6 polyunsaturated fatty acids diet (r = -0.43, P < 0.001) and high sodium diet (r = -0.62, P < 0.001) are negatively related to the incidence rate of elderly-AD.

CONCLUSION

The burden of elderly-AD is relatively high level in Europe with regional and gender disparities, and dietary habits are probably contributor.