Comparing content within a culturally-adapted digital treatment for Hispanic patients with alcohol use disorder.

Hispanic people in the U.S. experience alcohol-related harms comparable to non-Hispanic White people. Hispanic people often face more challenges to accessing alcohol use disorder (AUD) treatment. Culturally-adapted digital therapeutics may improve treatment access. Using data from two clinical trials of a culturally-adapted digital cognitive behavioral therapy program for Spanish-speaking Hispanic people (CBT4CBT-S, n = 43), we identified which program topics were most strongly linked to outcomes (NCT03474588 registered on 3/15/2018 and NCT02043210 registered on 1/10/2014 at clinicaltrials.gov). Topics were not administered in a randomized order. Participants drank less alcohol after completing content about coping with craving (OR = 0.48), cognitive restructuring (OR = 0.73), and problem solving (OR = 0.79). Participants were slightly more favorable towards content about cognitive restructuring (b = 0.14) and decision making (b = 0.09). These findings can inform further development of culturally-adapted digital therapeutics for AUD, which may improve alcohol-related health outcomes for Hispanic people.