Nonhepatic Manifestations of Alcohol Use Disorder and Alcohol-Related Liver Disease.

Alcohol use disorder (AUD) impacts many patients with alcohol-associated liver disease (ALD), affecting more than just the liver. ALD and AUD influence multiple organ systems, including neurologic, cardiovascular, gastrointestinal, hematologic, endocrine, and psychiatric. Recognizing these extrahepatic manifestations is essential for comprehensive patient care. Understanding how alcohol use affects these systems helps health care providers manage the full spectrum of health issues in patients with ALD. Addressing both liver-related and systemic effects of alcohol use ensures a more thorough and effective approach to treatment and patient outcomes.