Early diagnosis, treatment and prognosis of epilepsy with continuous spikes and waves during slow sleep.

The study is to investigate the importance of early diagnosis and treatment to the prognosis of epilepsy with continuous spikes and waves during slow sleep (CSWS). A total of 8 cases of CSWS children were followed up for 6 months to 4 years. Retrospective analysis of the clinical and electroencephalographic (EEG) characteristics, treatment and prognosis was performed in these 8 cases. Of the 8 cases of CSWS patients, 5 were males and 3 were females. Epilepsy onset ages were from 3 years and 1 month to 10 years and 6 months. Five cases of the patients were with brain lesions while the other 3 cases appeared normally by imaging detection. After treatment with valproic acid, clonazepam, lamotrigine and hormone for 3 months, clinical symptoms and EEG were improved significantly in 7 cases. Two cases relapsed at 6 months after comprehensive treatment. For atypical early performance of CSWS, early diagnosis and regular treatment could improve the condition of children with seizures and effectively inhibit the epileptic activity with good prognosis.