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DOI 10.7573/dic.2025-2-1

Медицинская библиотека · Drugs in context · 2025

Simulated client study on the dispensing practices for narcotic and psychotropic medications in community drug outlets in Ethiopia.

Zeleke Tirsit Ketsela, Worku Minichil Chanie, Tegegne Bantayehu Addis, Tamene Fasil Bayafers, Geremew Gebremariam Wulie, Wondm Samuel Agegnew, Tefera Aschalew Mulatu, Fitgu Ayelign Eshete, Alemayehu Tekletsadik Tekleslassie, Alemu Muluken Adela, Abebe Rahel Belete, Gubae Kale, Teym Abraham

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Аннотация

BACKGROUND

Dispensing prescription-only medications without a valid prescription poses significant public health risks, including inappropriate drug use, adverse drug reactions and medication dependence. Narcotics and psychotropic drugs are particularly vulnerable to misuse. Despite this, limited data exist on the dispensing practices of these medications at community drug retail outlets in Ethiopia. This study aimed to assess the extent and factors of non-prescription dispensing of narcotic and psychotropic medications at community drug retail outlets in Ethiopia.

METHODS

An observational cross-sectional study was conducted using the simulated client method from June 1, 2023, to September 30, 2023, in Debre Markos town, Ethiopia. Three trained volunteer pharmacy professionals acted as simulated clients. A validated simulated client approach was used to request medications through three different scenarios: symptom-based (depression), direct request by name and request by presenting a medication package.

RESULTS

A total of 109 requests were made by the simulated clients at 38 community drug retail outlets during three rounds of observations. The rates of non-prescription dispensing were 28.9% for depression simulation, 60.5% for direct name requests and 81.6% for package-based requests. A total of nine types of narcotic and psychotropic medications were dispensed without prescription, the most common of which were amitriptyline, followed by tramadol, carbamazepine, pethidine and haloperidol.

CONCLUSION

This study revealed a high prevalence of non-prescription dispensing of narcotic and psychotropic medications, particularly in response to assertive client requests. Urgent regulatory measures are needed to ensure adherence to prescription-only policies, especially for frequently dispensed drugs such as amitriptyline, tramadol and chlorpromazine.

Для цитирования: Zeleke Tirsit Ketsela, Worku Minichil Chanie, Tegegne Bantayehu Addis, Tamene Fasil Bayafers, Geremew Gebremariam Wulie, Wondm Samuel Agegnew, Tefera Aschalew Mulatu, Fitgu Ayelign Eshete, Alemayehu Tekletsadik Tekleslassie, Alemu Muluken Adela, Abebe Rahel Belete, Gubae Kale, Teym Abraham. Simulated client study on the dispensing practices for narcotic and psychotropic medications in community drug outlets in Ethiopia.. Drugs in context. 2025. DOI: 10.7573/dic.2025-2-1.
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