Journal of Korean medical science · 2009
Antihistamine pretreatment to reduce incidence of withdrawal movement after rocuronium injection.
СтатьяРандомизированное исследованиеНазвание и аннотация: Перевод в очереди
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Lee Ho Jun, Han Sung Jin, Kim Heezoo, Lee Il Ok, Kong Myoung Hoon, Kim Nan Suk, Lim Sang Ho, Lee Mi Kyoung
Аннотация
The purpose of this study was to determine the effectiveness of antihistamine therapy for withdrawal movements caused by rocuronium injection. One hundred seventy one ASA I-II adults undergoing elective surgery were randomly assigned to one of two groups. Patients in the control group (Group C) were premedicated with 2 mL normal saline, and those in the antihistamine group (Group A) were pre-medicated with 2 mL (45.5 mg) pheniramine maleate. After the administration of thiopental sodium 5 mg/kg, rocuronium 0.6 mg/kg was injected. Withdrawal movements were assessed using a four-grade scale. The administration of antihistamine reveals lower grade of withdrawal movement after rocuronium injection.