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DOI 10.1016/j.drugalcdep.2025.112666

Медицинская библиотека · Drug and alcohol dependence · 2025

Drug use and needle sharing among adolescents and young adults in Nigeria: A cross-sectional secondary analysis of data from a multi-site clinical trial.

Agunbiade Simisola, Gbaja-Biamila Titilola, Oladele David, Obiezu-Umeh Chisom, Musa Adesola Zaidat, Blessing Lateef Akeem, Tahlil Kadija Muse, Akinsolu Folahanmi Tomiwa, Conserve Donaldson F, Adeoti Ebenezer, Xian Hong, Kuriakose Kevin, Iwelunmor Juliet, Ezechi Oliver, Tucker Joseph

СтатьяМногоцентровое исследованиеПеревод в очереди

Аннотация

BACKGROUND

Adolescents and young adults (AYA, 14-24 years old) have the highest rates of drug use in most low- and middle-income countries. Little is known about the drivers of drug use among AYA in Nigeria and harm reduction services are limited.

METHODS

A secondary data analysis was performed of the baseline survey of the 'I-TEST' study involving AYA in Nigeria. The two primary outcomes of interest were lifetime measures of drug use and needle sharing. Logistic regression analyses were performed to obtain odds ratios for the associations between socio-demographic exposures and the two primary outcomes. Odds ratios were subsequently adjusted for age and sex.

RESULTS

1500 AYA survey responses were analysed. Respondents were mostly unemployed, students, and living in southern Nigeria. Drug use was reported by 301/1500(20.3 %) AYA. Among these, 213/301(71.5 %) reported needle sharing. Drug use did not vary by age (OR:0.94, 95 %CI:0.73-1.22) or sex (OR:1.00, 95 %CI:0.77-1.28). AYA in the North-Central zone had higher odds of drug use (OR:1.86, 95 %CI:1.28-2.69) and needle sharing (OR:2.51, 95 %CI:1.07-5.91) compared to AYA in the South-West zone of Nigeria. AYA aged 14-19 had higher odds of needle sharing compared to those aged 20-24 (OR:3.49, 95 %CI:1.94-6.26). Female AYA had higher odds of needle sharing compared to males (OR:5.05, 95 %CI:2.85-8.95).

CONCLUSIONS

Drug use and needle sharing are common among AYA in Nigeria. There is an urgent need for harm reduction services and research informed by AYA.

Для цитирования: Agunbiade Simisola, Gbaja-Biamila Titilola, Oladele David, Obiezu-Umeh Chisom, Musa Adesola Zaidat, Blessing Lateef Akeem, Tahlil Kadija Muse, Akinsolu Folahanmi Tomiwa, Conserve Donaldson F, Adeoti Ebenezer, Xian Hong, Kuriakose Kevin, Iwelunmor Juliet, Ezechi Oliver, Tucker Joseph. Drug use and needle sharing among adolescents and young adults in Nigeria: A cross-sectional secondary analysis of data from a multi-site clinical trial.. Drug and alcohol dependence. 2025. DOI: 10.1016/j.drugalcdep.2025.112666.

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