Diabetes, metabolic syndrome and obesity : targets and therapy · 2024
Effect of Preoperative Level of Glycemic Control with Pulsed Radiofrequency on the Incidence of Postherpetic Neuralgia in Patients with Herpes Zoster Combined with Type 2 Diabetes Mellitus: A Cohort Study.
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Hua Bohan, An Mingzi, Chen Liping, Ni Huadong, Ni Chaobo, Yao Ming
Аннотация
PURPOSE: To investigate the correlation between the level of glycosylated hemoglobin (HbA1c) and postherpetic neuralgia (PHN).
PATIENTS AND METHODS: This cohort study included 100 patients with herpes zoster (HZ) undergoing treatment with pulsed radiofrequency (PRF). Patients with comorbid type 2 diabetes mellitus (T2DM) were divided into three groups based on their glycemic control levels: good [HbA1c < 7% (53.01 mmol/mol), group D1], fair [7% (53.01 mmol/mol) ≤ HbA1c < 9% (74.86 mmol/mol), group D2], and poor [9% (74.86 mmol/mol) ≤ HbA1c, group D3]. The control group (group N) consisted of patients without T2DM. The main outcome measured was the occurrence of PHN in the four groups.
RESULTS: A total of 90 patients were included in the cohort. The occurrence of PHN was found to be higher in groups D2 and D3 when compared to group N (N vs D2, P = 0.007; N vs D3, P < 0.001). Furthermore, the occurrence of PHN was higher in groups D2 and D3 in comparison to group D1 (D1 vs D2, P = 0.022; D1 vs D3, P < 0.001), with the incidence of PHN in group D3 being greater than in group D2 (P < 0.001).
CONCLUSION: Preoperative HbA1c predicts the incidence of PHN after PRF in T2DM patients.
PATIENTS AND METHODS: This cohort study included 100 patients with herpes zoster (HZ) undergoing treatment with pulsed radiofrequency (PRF). Patients with comorbid type 2 diabetes mellitus (T2DM) were divided into three groups based on their glycemic control levels: good [HbA1c < 7% (53.01 mmol/mol), group D1], fair [7% (53.01 mmol/mol) ≤ HbA1c < 9% (74.86 mmol/mol), group D2], and poor [9% (74.86 mmol/mol) ≤ HbA1c, group D3]. The control group (group N) consisted of patients without T2DM. The main outcome measured was the occurrence of PHN in the four groups.
RESULTS: A total of 90 patients were included in the cohort. The occurrence of PHN was found to be higher in groups D2 and D3 when compared to group N (N vs D2, P = 0.007; N vs D3, P < 0.001). Furthermore, the occurrence of PHN was higher in groups D2 and D3 in comparison to group D1 (D1 vs D2, P = 0.022; D1 vs D3, P < 0.001), with the incidence of PHN in group D3 being greater than in group D2 (P < 0.001).
CONCLUSION: Preoperative HbA1c predicts the incidence of PHN after PRF in T2DM patients.