Internal medicine (Tokyo, Japan) · 2019
Varicella-zoster Virus Related Pulmonary Granulomas in Which Varicella-zoster Virus DNA Was Demonstrated in a Thoracoscopic Lung Biopsy Specimen.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Isobe Takeshi, Umemoto Jyunro, Kobayashi Misato, Okuno Takae, Shiratsuki Youhei, Kodama Akari, Nakao Mika, Amano Yoshihiro, Hotta Takamasa, Hamaguchi Megumi, Okimoto Tamio, Hamaguchi Shunichi, Tsubata Yukari
Аннотация
A 43-year-old man with malignant lymphoma who had been treated with the cyclosphamide, vincrstine, procarbazine, and prednisolone (C-MOPP) regimen was admitted to our hospital with skin eruption. He was diagnosed to have varicella, and treatment with acyclovir and immune globulin was started. Chest computed tomography revealed multiple nodules in the both lung fields. Diagnostic thoracoscopic lung biopsy specimens revealed granuloma formation, and polymerase chain reaction testing revealed the presence of varicella-zoster virus DNA in the granulomatous tissue. It was unusual for the lung nodule in varicella pneumonia to increase in size over time in a patient who had undergone antiviral therapy, while also demonstrating multiple granulomas.