[Reproductive Risk Factors For Breast Cancer: A Case-Control Study].

UNLABELLED: Breast cancer is the leading cancer in Mali. The objective of this study was to evaluate the risk factors of breast cancer associated with reproduction.

PATIENTS AND

METHODS

We conducted a case-control study (January 2017 - September 2021) at the Gabriel Touré Teaching Hospital. The sample consisted of 200 cases and 400 controls. A multivariable logistic regression model was used to identify reproductive factors associated with breast cancer. Adjusted odds ratios (AOR) were produced with their 95% confidence intervals.

RESULTS

The mean age of cases was 46.1 years ± 14.6 vs 33.1 years ± 12.1 for controls. Menopausal women constituted 37.5 % of cases vs only 4% in the controls group. Nulliparity and breastfeeding were negatively associated with breast cancer (p <0,001) while postmenopausal women had a8.09-fold increase in the risk of breast cancer.

CONCLUSION

Nulliparity, breastfeeding and menopause were the reproductive factors associated with breast cancer in Mali.