Journal of the National Comprehensive Cancer Network : JNCCN · 2016
Genetic/Familial High-Risk Assessment: Breast and Ovarian, Version 2.2015.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Daly Mary B, Pilarski Robert, Axilbund Jennifer E, Berry Michael, Buys Saundra S, Crawford Beth, Farmer Meagan, Friedman Susan, Garber Judy E, Khan Seema, Klein Catherine, Kohlmann Wendy, Kurian Allison, Litton Jennifer K, Madlensky Lisa, Marcom P Kelly, Merajver Sofia D, Offit Kenneth, Pal Tuya, Rana Huma, Reiser Gwen, Robson Mark E, Shannon Kristen Mahoney, Swisher Elizabeth, Voian Nicoleta C, Weitzel Jeffrey N, Whelan Alison, Wick Myra J, Wiesner Georgia L, Dwyer Mary, Kumar Rashmi, Darlow Susan
Аннотация
The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Breast and Ovarian provide recommendations for genetic testing and counseling and risk assessment and management for hereditary cancer syndromes. Guidelines focus on syndromes associated with an increased risk of breast and/or ovarian cancer and are intended to assist with clinical and shared decision-making. These NCCN Guidelines Insights summarize major discussion points of the 2015 NCCN Genetic/Familial High-Risk Assessment: Breast and Ovarian panel meeting. Major discussion topics this year included multigene testing, risk management recommendations for less common genetic mutations, and salpingectomy for ovarian cancer risk reduction. The panel also discussed revisions to genetic testing criteria that take into account ovarian cancer histology and personal history of pancreatic cancer.