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DOI 10.1590/s0004-2803.24612026-034

Медицинская библиотека · Arquivos de gastroenterologia · 2026

IMPACT OF PERCUTANEOUS ENDOSCOPIC GASTROSTOMY ON THE ESOPHAGEAL/GASTRIC MUCOSA AND HELICOBACTER PYLORI IN INDIVIDUALS WITH NEUROGENIC OROPHARYNGEAL DYSPHAGIA.

Pilon João Paulo Galletti, Medeiros Rodolfo de Oliveira, Cola Paula Cristina, Onofri Suely Mayumi Motonaga

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Аннотация

BACKGROUND

Oropharyngeal dysphagia is frequent among individuals with neurological disorders and may impair nutrition and quality of life. Long-term nasoenteric tube use is associated with esophagitis, gastritis, and increased Helicobacter pylori, highlighting the need for safer nutritional alternatives. Percutaneous endoscopic gastrostomy (PEG) is widely used for long-term enteral feeding.

OBJECTIVE

To evaluate esophageal and gastric inflammatory changes and the presence of H. pylori before and 6 months after PEG placement in patients with neurogenic oropharyngeal dysphagia.

MATERIALS AND

METHODS

In this prospective study, 42 patients (median age 76 years) underwent upper gastrointestinal endoscopy and rapid urease testing at baseline and six months after PEG placement. Esophagitis and gastritis were classified using the Los Angeles and Sydney systems. McNemar test was applied (P≤0.05).

RESULTS

Esophagitis decreased from 57% to 5% and gastritis from 52% to 10% (both P<0.001). H. pylori positivity declined from 24% to 12% (P=0.154).

CONCLUSION

PEG was associated with significant improvement in esophageal and gastric mucosal integrity, supporting its role as a safe long-term nutritional strategy in patients with neurogenic oropharyngeal dysphagia.

Для цитирования: Pilon João Paulo Galletti, Medeiros Rodolfo de Oliveira, Cola Paula Cristina, Onofri Suely Mayumi Motonaga. IMPACT OF PERCUTANEOUS ENDOSCOPIC GASTROSTOMY ON THE ESOPHAGEAL/GASTRIC MUCOSA AND HELICOBACTER PYLORI IN INDIVIDUALS WITH NEUROGENIC OROPHARYNGEAL DYSPHAGIA.. Arquivos de gastroenterologia. 2026. DOI: 10.1590/s0004-2803.24612026-034.

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