Essential data dimensions for prospective international data collection in older age bipolar disorder (OABD): Recommendations from the GAGE-BD group.
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Lavin Paola, Rej Soham, Olagunju Andrew T, Teixeira Antonio L, Dols Annemieke, Alda Martin, Almeida Osvaldo P, Altinbas Kursat, Balanzá-Martínez Vicent, Barbosa Izabela G, Blumberg Hilary P, Briggs Farren, Calkin Cynthia, Cassidy Kristin, Forester Brent P, Forlenza Orestes V, Hajek Tomas, Haarman Barthomeus C M, Jimenez Esther, Lafer Beny, Mulsant Benoit, Oluwaniyi Stephen O, Patrick Regan, Radua Joaquim, Schouws Sigfried, Sekhon Harmehr, Simhandl Christian, Soares Jair C, Tsai Shang-Ying, Vieta Eduard, Villa Luca M, Sajatovic Martha, Eyler Lisa T
Аннотация
METHODS: We developed initial recommendations for the essential dimensions for OABD data collection, based on (1) a systematic review of measures used in OABD studies, (2) a Delphi consensus of international OABD experts, (3) experience with harmonizing OABD data in the Global Aging & Geriatric Experiments in Bipolar Disorder Database (GAGE-BD, n ≥ 4500 participants), and (4) critical feedback from 34 global experts in geriatric mental health.
RESULTS: We identified 15 key dimensions and variables within each that are relevant for the investigation of OABD: (1) demographics, (2) core symptoms of depression and (3) mania, (4) cognition screening and subjective cognitive function, (5) elements for BD diagnosis, (6) descriptors of course of illness, (7) treatment, (8) suicidality, (9) current medication, (10) psychiatric comorbidity, (11) psychotic symptoms, (12) general medical comorbidities, (13) functioning, (14) family history, and (15) other. We also recommend particular instruments for capturing some of the dimensions and variables.
CONCLUSION: The essential data dimensions we present should be of use to guide future international data collection in OABD and clinical practice. In the longer term, we aim to establish a prospective consortium using this core set of dimensions and associated variables to answer research questions relevant to OABD.