Delayed progression and inefficient transmission of HIV-2.

We report a case of HIV-2 infection with delayed progression, taking approximately one and a half decades to develop HIV related symptoms. The spouse was still negative for HIV with a history of having regular unprotected sex with the index case which highlights the inefficient transmissibility of HIV-2. Continued surveillance is needed in screening of HIV-2 infection, especially in cases with a high index of suspicion and risk factors for HIV-2, as these patients develop AIDS related symptoms quite late due to delayed progression.