Archivos espanoles de urologia · 1995
[The dissolution of cystine lithiasis with n-acetylcysteine].
Клинический случайАннотация на английскомСтатьяОбзорНазвание и аннотация: Перевод в очереди
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Benítez Navio J, Tudela Pavón P, Laguna Urraca G, Casanueva Luis T, Ruana Encinar M, Mata Guijarro F, Gallardo Galán C
Аннотация
OBJECTIVE: The results of in situ dissolution of a cystine calculus is described. This approach was attempted in a female patient for whom surgery was not considered to be the best therapeutic option.
METHODS: An obstructive cystine calculus was treated by in situ litholysis using N-acetylcysteine applied locally via two percutaneous nephrostomies and adjuvant oral metaphylaxis. The patient had a long clinical history of lithiasis that had also required surgery and a family history of cystinuria.
RESULTS: In situ litholysis completely dissolved the cystine calculus and avoided the need for a complex surgery. The procedure and a pharmacological analysis are presented.
CONCLUSIONS: In our view, this procedure is practical, carries minimal morbidity and should be considered in the management of cystine calculus.
METHODS: An obstructive cystine calculus was treated by in situ litholysis using N-acetylcysteine applied locally via two percutaneous nephrostomies and adjuvant oral metaphylaxis. The patient had a long clinical history of lithiasis that had also required surgery and a family history of cystinuria.
RESULTS: In situ litholysis completely dissolved the cystine calculus and avoided the need for a complex surgery. The procedure and a pharmacological analysis are presented.
CONCLUSIONS: In our view, this procedure is practical, carries minimal morbidity and should be considered in the management of cystine calculus.