BMJ open gastroenterology · 2024
Increased rate of pancreatitis in gender diverse and transgender patients on hormone therapy: a case series study.
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Podboy Alexander, Casey Catherine, Buerlein Ross C D, Strand Daniel S, Shami Vanessa M, Wang Andrew Y
Аннотация
BACKGROUND: There is limited data on the incidence of gastrointestinal-specific pathology in gender non-conforming (GNC) populations.
METHODS: Retrospective analysis of pancreatitis incidence rates in transgender and GNC persons exposed and not exposed to gender-affirming hormone therapy (GAHT).
RESULTS: 7 of the 1333 patients on hormone therapy had an incidence of pancreatitis. 0 of the 615 patients with no history of GAHT use developed pancreatitis. Representing a 6.96 (95% CI 2.76 to 848.78) for the development of pancreatitis in patients with exposure to GAHT therapy.
CONCLUSION: Clinicians working with GNC individuals should be aware of this possible association.
METHODS: Retrospective analysis of pancreatitis incidence rates in transgender and GNC persons exposed and not exposed to gender-affirming hormone therapy (GAHT).
RESULTS: 7 of the 1333 patients on hormone therapy had an incidence of pancreatitis. 0 of the 615 patients with no history of GAHT use developed pancreatitis. Representing a 6.96 (95% CI 2.76 to 848.78) for the development of pancreatitis in patients with exposure to GAHT therapy.
CONCLUSION: Clinicians working with GNC individuals should be aware of this possible association.