Acta haematologica · 2014
Successful treatment of refractory Guillain-Barré syndrome with alemtuzumab in a patient with chronic lymphocytic leukemia.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Tzachanis Dimitrios, Hamdan Ayad, Uhlmann Erik J, Joyce Robin M
Аннотация
This is the case of a 79-year-old man with chronic lymphocytic leukemia who presented with Guillain-Barré syndrome with features overlapping with the Miller Fisher syndrome and Bickerstaff brainstem encephalitis and positive antiganglioside GQ1b antibody about 6 months after treatment with bendamustine and rituximab. His clinical and neurologic condition continued to deteriorate despite sequential treatment with corticosteroids, intravenous immunoglobulin and plasmapheresis, but in the end, he had a complete and durable response to treatment with alemtuzumab.
Предметные рубрики MeSH
AgedAlemtuzumabAntibodies, Monoclonal, HumanizedAntibodies, Monoclonal, Murine-DerivedAntigens, CDAntigens, NeoplasmAntineoplastic Combined Chemotherapy ProtocolsAutoantibodiesAutoantigensBendamustine HydrochlorideCD52 AntigenCombined Modality TherapyConsciousness DisordersGangliosidesGlycoproteinsGuillain-Barre SyndromeHerpes ZosterHerpesvirus 3, HumanHumansImmunoglobulins, IntravenousLeukemia, Lymphocytic, Chronic, B-CellMaleMethylprednisoloneMiller Fisher SyndromeNitrogen Mustard CompoundsPlasmapheresisRemission InductionRituximabVirus Activation