Gastrointestinal endoscopy · 2007
Colorectal neoplasm in asymptomatic Asians: a prospective multinational multicenter colonoscopy survey.
СтатьяМногоцентровое исследованиеНазвание и аннотация: Перевод в очереди
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Byeon Jeong-Sik, Yang Suk-Kyun, Kim Tae Il, Kim Won Ho, Lau James Y W, Leung Wai-Keung, Fujita Rikiya, Makharia Govind K, Abdullah Murdan, Hilmi Ida, Sollano Jose, Yeoh Khay-Guan, Wu Deng-Chyang, Chen Min Hu, Kongkam Pradermchai, Sung Joseph J Y, Asia Pacific Working Group for Colorectal Cancer
Аннотация
BACKGROUND: Colorectal neoplasm is rapidly increasing in Asia, but a guideline for screening is not available.
OBJECTIVE: To evaluate the characteristics of colorectal neoplasm in asymptomatic Asian subjects.
DESIGN: Prospective cohort study.
SETTING: Multinational multicenters, including both primary and referral centers in Asia.
PATIENTS: A total of 860 consecutive asymptomatic adults undergoing screening colonoscopy in 11 Asian cities from July 2004 to December 2004. Patients under 16 years old; those patients with a colorectal resection history, colonoscopies, or barium enema within 5 years; symptoms suggestive of colorectal diseases; and those who had undergone surveillance colonoscopy were excluded.
MAIN OUTCOME MEASUREMENTS: The incidence and distribution of colorectal neoplasm and advanced neoplasm.
RESULTS: The mean age (+/-SD) was 54.4+/-11.6 years; 471 were men (54.8%). The prevalence of colorectal neoplasm and advanced neoplasm was 18.5% and 4.5%, respectively. Male sex, advancing age, and a family history of colorectal cancer were risk factors for advanced neoplasm. Of the 168 patients with colorectal neoplasm, 76 had distal neoplasm only (45.2%), 66 had proximal neoplasm only (39.3%), and 26 had both proximal and distal neoplasms (15.5%). Although the presence of distal advanced neoplasm was a significant risk factor for proximal advanced neoplasm, 14 of the 758 subjects without distal neoplasm had proximal advanced neoplasm (1.8%).
LIMITATIONS: The small number of enrolled subjects, especially from certain ethnic groups.
CONCLUSIONS: The overall prevalence of advanced colorectal neoplasm in asymptomatic Asians is comparable with the West. Male sex, advancing age, and a family history of colorectal cancer were associated with a higher risk of advanced neoplasm.
OBJECTIVE: To evaluate the characteristics of colorectal neoplasm in asymptomatic Asian subjects.
DESIGN: Prospective cohort study.
SETTING: Multinational multicenters, including both primary and referral centers in Asia.
PATIENTS: A total of 860 consecutive asymptomatic adults undergoing screening colonoscopy in 11 Asian cities from July 2004 to December 2004. Patients under 16 years old; those patients with a colorectal resection history, colonoscopies, or barium enema within 5 years; symptoms suggestive of colorectal diseases; and those who had undergone surveillance colonoscopy were excluded.
MAIN OUTCOME MEASUREMENTS: The incidence and distribution of colorectal neoplasm and advanced neoplasm.
RESULTS: The mean age (+/-SD) was 54.4+/-11.6 years; 471 were men (54.8%). The prevalence of colorectal neoplasm and advanced neoplasm was 18.5% and 4.5%, respectively. Male sex, advancing age, and a family history of colorectal cancer were risk factors for advanced neoplasm. Of the 168 patients with colorectal neoplasm, 76 had distal neoplasm only (45.2%), 66 had proximal neoplasm only (39.3%), and 26 had both proximal and distal neoplasms (15.5%). Although the presence of distal advanced neoplasm was a significant risk factor for proximal advanced neoplasm, 14 of the 758 subjects without distal neoplasm had proximal advanced neoplasm (1.8%).
LIMITATIONS: The small number of enrolled subjects, especially from certain ethnic groups.
CONCLUSIONS: The overall prevalence of advanced colorectal neoplasm in asymptomatic Asians is comparable with the West. Male sex, advancing age, and a family history of colorectal cancer were associated with a higher risk of advanced neoplasm.