Journal of medical imaging (Bellingham, Wash.) · 2025
Mpox lesion counting with semantic and instance segmentation methods.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Jiang Bohan, McNeil Andrew J, Liu Yihao, House David W, Mbala-Kingebeni Placide, Mbaya Olivier Tshiani, Silaphet Tyra, Dodd Lori E, Cowen Edward W, Nussenblatt Veronique, Bonnett Tyler, Chen Ziche, Saknite Inga, Dawant Benoit M, Tkaczyk Eric R
Аннотация
PURPOSE: Mpox is a viral illness with symptoms similar to smallpox. A key clinical metric to monitor disease progression is the number of skin lesions. Manually counting mpox skin lesions is labor-intensive and susceptible to human error.
APPROACH: We previously developed an mpox lesion counting method based on the UNet segmentation model using 66 photographs from 18 patients. We have compared four additional methods: the instance segmentation methods Mask R-CNN, YOLOv8, and E2EC, in addition to a UNet++ model. We designed a patient-level leave-one-out experiment, assessing their performance using F 1 score and lesion count metrics. Finally, we tested whether an ensemble of the networks outperformed any single model.
RESULTS: Mask R-CNN model achieved an F 1 score of 0.75, YOLOv8 a score of 0.75, E2EC a score of 0.70, UNet++ a score of 0.81, and baseline UNet a score of 0.79. Bland-Altman analysis of lesion count performance showed a limit of agreement (LoA) width of 62.2 for Mask R-CNN, 91.3 for YOLOv8, 94.2 for E2EC, and 62.1 for UNet++, with the baseline UNet model achieving 69.1. The ensemble showed an F 1 score performance of 0.78 and LoA width of 67.4.
CONCLUSIONS: Instance segmentation methods and UNet-based semantic segmentation methods performed equally well in lesion counting. Furthermore, the ensemble of the trained models showed no performance increase over the best-performing model UNet, likely because errors are frequently shared across models. Performance is likely limited by the availability of high-quality photographs for this complex problem, rather than the methodologies used.
APPROACH: We previously developed an mpox lesion counting method based on the UNet segmentation model using 66 photographs from 18 patients. We have compared four additional methods: the instance segmentation methods Mask R-CNN, YOLOv8, and E2EC, in addition to a UNet++ model. We designed a patient-level leave-one-out experiment, assessing their performance using F 1 score and lesion count metrics. Finally, we tested whether an ensemble of the networks outperformed any single model.
RESULTS: Mask R-CNN model achieved an F 1 score of 0.75, YOLOv8 a score of 0.75, E2EC a score of 0.70, UNet++ a score of 0.81, and baseline UNet a score of 0.79. Bland-Altman analysis of lesion count performance showed a limit of agreement (LoA) width of 62.2 for Mask R-CNN, 91.3 for YOLOv8, 94.2 for E2EC, and 62.1 for UNet++, with the baseline UNet model achieving 69.1. The ensemble showed an F 1 score performance of 0.78 and LoA width of 67.4.
CONCLUSIONS: Instance segmentation methods and UNet-based semantic segmentation methods performed equally well in lesion counting. Furthermore, the ensemble of the trained models showed no performance increase over the best-performing model UNet, likely because errors are frequently shared across models. Performance is likely limited by the availability of high-quality photographs for this complex problem, rather than the methodologies used.