International journal of clinical and experimental medicine · 2012
Early-onset breast disease: case of a Grave condition with a favorable prognosis.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Siegler James E, Jones Steven D, Kandil Emad
Аннотация
BACKGROUND: The relationship between thyroid and breast diseases has been well documented, but the clinical impact of Graves' disease on breast tissue is not clear.
PATIENT FINDINGS: Twenty-seven year-old African American female patient who presented with multiple bilateral breast masses and skin thickening and ulcerations. Biopsy of the breast masses demonstrated fat necrosis. During her initial evaluation, she was found to be hyperthyroid and was ultimately diagnosed with Graves' disease. Her abnormal breast changes resolved within several months of her medical treatment for Graves' disease.
SUMMARY: Graves' disease may present with acute-onset breast changes without personal history of trauma or family history of breast abnormalities.
CONCLUSIONS: Interactions between thyroid and estrogen hormones should be studied further to determine their exact clinical and pathologic implications. Medical or surgical management of Graves' disease may reverse associated pathologic breast changes.
PATIENT FINDINGS: Twenty-seven year-old African American female patient who presented with multiple bilateral breast masses and skin thickening and ulcerations. Biopsy of the breast masses demonstrated fat necrosis. During her initial evaluation, she was found to be hyperthyroid and was ultimately diagnosed with Graves' disease. Her abnormal breast changes resolved within several months of her medical treatment for Graves' disease.
SUMMARY: Graves' disease may present with acute-onset breast changes without personal history of trauma or family history of breast abnormalities.
CONCLUSIONS: Interactions between thyroid and estrogen hormones should be studied further to determine their exact clinical and pathologic implications. Medical or surgical management of Graves' disease may reverse associated pathologic breast changes.