[Vascular risk factors in non-insulin-dependent diabetes mellitus. Correlation between albuminuria and glycosylated hemoglobin].

OBJECTIVE

This study compared 23 patients with non-insulin-dependent diabetes mellitus (NIDDM) and 28 non-diabetic control subjects, seeking for associations between NIDDM and other cardiovascular risk factors. The relationship of the glycemic control with the risk factor profile was also assessed.

RESULTS

The most outstanding results were: The diabetic group showed higher values in the proportion of subjects with diabetes family history (P < 0.01) and the levels of systolic blood pressure (P < 0.05), total cholesterol (P < 0.05), triglyceridemia (P < 0.001), and total cholesterol to HDL cholesterol ratio (P < 0.01). Within the diabetic group, a positive correlation (r = 0.68, P < 0.001) was found between the percent of glycosylated haemoglobin (HbA1c) and the 24-hour urinary albumin excretion rate (UAER).

CONCLUSION

We conclude that NIDDM associates to other cardiovascular risk factors. The correlation of HbA1c with UAER suggests a possible relationship between poor diabetic control and some of the secondary diabetic complications.