PloS one · 2025
Estimating the impact of missed colorectal cancer diagnoses on life expectancy in Minamisoma City following the 2011 triple disaster.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Saito Hiroaki, Murakami Michio, Ozaki Akihiko, Nishikawa Yoshitaka, Sawano Toyoaki, Shimada Yuki, Fujioka Sho, Zhao Tianchen, Oikawa Tomoyoshi, Kanazawa Yukio, Tsubokura Masaharu
Аннотация
BACKGROUND: After the 2011 Great East Japan Earthquake, participation in colorectal cancer (CRC) screening significantly decreased in Minamisoma City, Fukushima Prefecture. However, the long-term health effects of this decline in screening participation have not been quantified. This study aims to construct a model to evaluate the impact of post-disaster decreases in CRC screening participation on population health.
METHODS: We utilized the population and CRC screening data targeting 40-74 years-old residents in Minamisoma City. We compared the actual screening participation in 2011 with projected participation rates based on pre-disaster levels to estimate the number of residents who missed screening due to the disaster. Based on national CRC screening performance data and stage-specific survival rates in Japan, we estimated the number of missed CRC cases and modeled the additional the loss of life expectancy (LLE) due to CRC resulting from a one-year delay in diagnosis.
RESULTS: The estimated number of colorectal cancer cases that might have been missed due to decreased screening participation was 1.794 (95% uncertainty interval: 1.597 to 1.994) for men and 1.203 (0.931 to 1.491) for women. The missed detection opportunities estimated result in 0.428 (0.282 to 0.582) person-years [2.684 (1.793 to 3.604) years per 10,000 persons] and 0.229 (0.103 to 0.372) person-years [0.993 (0.450 to 1.608) years per 10,000 persons] of additional LLE for men and women, respectively. The estimated cost per life-year saved was [Formula: see text]yen for men and [Formula: see text] yen for women, respectively.
CONCLUSIONS: The calculated additional LLE due to missed CRC screening was relatively small but suggests preventive health services should be considered in disaster response planning. These findings provide a quantitative framework for evaluating health impacts of service disruptions.
METHODS: We utilized the population and CRC screening data targeting 40-74 years-old residents in Minamisoma City. We compared the actual screening participation in 2011 with projected participation rates based on pre-disaster levels to estimate the number of residents who missed screening due to the disaster. Based on national CRC screening performance data and stage-specific survival rates in Japan, we estimated the number of missed CRC cases and modeled the additional the loss of life expectancy (LLE) due to CRC resulting from a one-year delay in diagnosis.
RESULTS: The estimated number of colorectal cancer cases that might have been missed due to decreased screening participation was 1.794 (95% uncertainty interval: 1.597 to 1.994) for men and 1.203 (0.931 to 1.491) for women. The missed detection opportunities estimated result in 0.428 (0.282 to 0.582) person-years [2.684 (1.793 to 3.604) years per 10,000 persons] and 0.229 (0.103 to 0.372) person-years [0.993 (0.450 to 1.608) years per 10,000 persons] of additional LLE for men and women, respectively. The estimated cost per life-year saved was [Formula: see text]yen for men and [Formula: see text] yen for women, respectively.
CONCLUSIONS: The calculated additional LLE due to missed CRC screening was relatively small but suggests preventive health services should be considered in disaster response planning. These findings provide a quantitative framework for evaluating health impacts of service disruptions.