Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2012
History of major depressive disorder prospectively predicts worse quality of life in women with breast cancer.
СтатьяПоддержка NIH: внешняя программаНазвание и аннотация: Перевод в очереди
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Jim Heather S L, Small Brent J, Minton Susan, Andrykowski Michael, Jacobsen Paul B
Аннотация
BACKGROUND: Data are scarce about whether past history of major depressive disorder in the absence of current depression places breast cancer patients at risk for worse quality of life.
PURPOSE: The current study prospectively examined quality of life during chemotherapy in breast cancer patients with a history of resolved major depressive disorder (n = 29) and no history of depression (n = 144).
METHODS: Women with Stages 0-II breast cancer were assessed prior to and at the completion of chemotherapy. Major depressive disorder was assessed via structured interview and quality of life with the SF-36.
RESULTS: Patients with past major depressive disorder displayed greater declines in physical functioning relative to patients with no history of depression (p ≤ 0.01).
CONCLUSIONS: Findings suggest that breast cancer patients with a history of resolved major depressive disorder are at increased risk for declines in physical functioning during chemotherapy relative to patients with no history of depression.
PURPOSE: The current study prospectively examined quality of life during chemotherapy in breast cancer patients with a history of resolved major depressive disorder (n = 29) and no history of depression (n = 144).
METHODS: Women with Stages 0-II breast cancer were assessed prior to and at the completion of chemotherapy. Major depressive disorder was assessed via structured interview and quality of life with the SF-36.
RESULTS: Patients with past major depressive disorder displayed greater declines in physical functioning relative to patients with no history of depression (p ≤ 0.01).
CONCLUSIONS: Findings suggest that breast cancer patients with a history of resolved major depressive disorder are at increased risk for declines in physical functioning during chemotherapy relative to patients with no history of depression.