Onkologie · 2008
Cancer of the urinary bladder neovagina in a patient with Morris' syndrome.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Wielgos Miroslaw, Szymusik Iwona, Banaszek Agnieszka, Suchonska Barbara, Kaminski Pawel, Gadomska Halina, Bablok Leszek
Аннотация
BACKGROUND: Vaginal agenesis is a rare condition, therefore the incidence of a malignant transformation in the neovagina is extremely low.
CASE REPORT: We report on a 42-year-old patient with Morris' syndrome and urinary bladder neovagina with a history of prolonged infections of the urinary bladder and intertrigo of the perineal region. The biopsy revealed a squamous cell carcinoma arising from the neovagina. The patient underwent combined radio- and chemotherapy and was disqualified from surgical treatment because of the advanced stage of the disease.
CONCLUSIONS: Because of the high risk of malignant transformations regular follow-ups are necessary in patients with neovagina creation, including gynecological examination, cytological screening, and biopsy if necessary. In addition, urinary bladder does not seem to be a good material for a functional vagina.
CASE REPORT: We report on a 42-year-old patient with Morris' syndrome and urinary bladder neovagina with a history of prolonged infections of the urinary bladder and intertrigo of the perineal region. The biopsy revealed a squamous cell carcinoma arising from the neovagina. The patient underwent combined radio- and chemotherapy and was disqualified from surgical treatment because of the advanced stage of the disease.
CONCLUSIONS: Because of the high risk of malignant transformations regular follow-ups are necessary in patients with neovagina creation, including gynecological examination, cytological screening, and biopsy if necessary. In addition, urinary bladder does not seem to be a good material for a functional vagina.
Предметные рубрики MeSH
AdultAndrogen-Insensitivity SyndromeBiopsyCarcinoma, Squamous CellCell Transformation, NeoplasticCisplatinCombined Modality TherapyDisease ProgressionFemaleHumansMaleNeoplasm InvasivenessNeoplasm StagingPelvisPostoperative ComplicationsRadioisotope TeletherapyPlastic Surgery ProceduresSurgical FlapsSyndromeUrinary BladderVaginaVaginal Neoplasms