The historical development and current status of the China Marrow Donor Program.

There are about 50,000 new leukemia patients each year in China. The Chinese government has funded the CMDP since 2001. So far, there are 1,471,212 volunteer donors registered in CMDP with HLA-A, B, DR typing. Of the donors, 25.85% were typed with high-resolution results. The typing error rate has decreased from 8.18% in 2003, to 0.4% in 2011. So far, 2,700 patients, including patients outside of China, have received stem cells from the CMDP. The overall one-year survival is about 70%. Since 2006, 42% of patients have received HLA-A, B, C, DR, DQ identical (10/10) transplants and 37.5% of patients have received 9/10 transplants. The one-year survival with 10/10 is 71% and 72% for 9/10 transplants. The efforts of the past 10 years have laid a foundation for the CMDP's further development. We expect that more patients' lives will be saved through these efforts.