American journal of ophthalmology · 2005
Corneal pseudomembrane from acute inflammatory response and fibrin formation to acute myeloid leukemic infiltrate.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Kurup Shree K, Coleman Hanna, Chan Chi-Chao
Аннотация
PURPOSE: To describe an unusual ocular manifestation of a patient with acute myeloid leukemia (AML).
DESIGN: Observational case report.
METHODS: A 59-year-old woman with a history of preleukemic myelodysplastic syndrome (MDS) and status post bone marrow transplant (BMT) complained of a sudden onset of poor vision associated with a corneal pseudomembrane. Ocular graft vs host disease was suspected, and the pseudomembrane was excised for histopathologic examination.
RESULTS: The pseudomembrane showed myeloblasts admixed with an acute inflammatory response suggestive of the development of AML, a complication of MDS. Bone marrow examination confirmed the diagnosis of relapsing AML.
CONCLUSIONS: Acute myeloid leukemia could present as a pseudomembrane; thus, examination of relevant ocular tissue is recommended.
DESIGN: Observational case report.
METHODS: A 59-year-old woman with a history of preleukemic myelodysplastic syndrome (MDS) and status post bone marrow transplant (BMT) complained of a sudden onset of poor vision associated with a corneal pseudomembrane. Ocular graft vs host disease was suspected, and the pseudomembrane was excised for histopathologic examination.
RESULTS: The pseudomembrane showed myeloblasts admixed with an acute inflammatory response suggestive of the development of AML, a complication of MDS. Bone marrow examination confirmed the diagnosis of relapsing AML.
CONCLUSIONS: Acute myeloid leukemia could present as a pseudomembrane; thus, examination of relevant ocular tissue is recommended.