Journal francais d'ophtalmologie · 2011
[Reversible optic neuropathy related to disulfiram].
Клинический случайАннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
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Trélohan A, Milea D
Аннотация
OBJECTIVE: To report a case of bilateral optic neuropathy, possibly caused by disulfiram.
PATIENTS AND METHODS: Clinical case report.
RESULTS: A 46-year-old patient, treated with disulfiram for the past 4 years for chronic alcoholism, presented with progressive bilateral, painless, severe visual loss, related to optic neuropathy. An extensive work-up did not disclose any other possible cause than a toxic optic neuropathy caused by disulfiram. Discontinuation of disulfiram resulted in rapid, complete visual recovery.
CONCLUSION: Disulfiram can cause toxic optic neuropathy, which can recover after discontinuing the medication, even after a long period of intoxication.
PATIENTS AND METHODS: Clinical case report.
RESULTS: A 46-year-old patient, treated with disulfiram for the past 4 years for chronic alcoholism, presented with progressive bilateral, painless, severe visual loss, related to optic neuropathy. An extensive work-up did not disclose any other possible cause than a toxic optic neuropathy caused by disulfiram. Discontinuation of disulfiram resulted in rapid, complete visual recovery.
CONCLUSION: Disulfiram can cause toxic optic neuropathy, which can recover after discontinuing the medication, even after a long period of intoxication.