[Reversible optic neuropathy related to disulfiram].

OBJECTIVE

To report a case of bilateral optic neuropathy, possibly caused by disulfiram.

PATIENTS AND

METHODS

Clinical case report.

RESULTS

A 46-year-old patient, treated with disulfiram for the past 4 years for chronic alcoholism, presented with progressive bilateral, painless, severe visual loss, related to optic neuropathy. An extensive work-up did not disclose any other possible cause than a toxic optic neuropathy caused by disulfiram. Discontinuation of disulfiram resulted in rapid, complete visual recovery.

CONCLUSION

Disulfiram can cause toxic optic neuropathy, which can recover after discontinuing the medication, even after a long period of intoxication.