Disulfiram revisited.

Disulfiram can be important in helping motivated alcoholics to remain abstinent. Prescribers should be aware of disulfiram's toxicity, and how to recognize and manage reactions. A number of other agents are available to help alcoholics remain sober, although these do not necessarily obviate use of disulfiram. Also, disulfiram may have a wider role in the management of the addictions, e.g. in cocaine use.