Pharmaceutics · 2025
The Potential of Amphiphilic Cyclodextrins as Carriers for Therapeutic Purposes: A Short Overview.
СтатьяОбзорНазвание и аннотация: Перевод в очереди
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Pârvănescu Ramona Daniela, Păpurică Marius, Alexa Ionica Oana, Dehelean Cristina Adriana, Șoica Codruța, Moacă Elena Alina, Ledeți Adriana, Voicu Mirela, Coricovac Dorina, Trandafirescu Cristina
Аннотация
Cyclodextrins, since their discovery in the late 19th century, have gained tremendous interest in biomedical research, beginning with their recognition as safe pharmaceutical excipients, and continuing with exploiting their potential for enhancing the therapeutic response of active pharmaceutical ingredients, and also to be used as drugs for specific medical purposes. This review presents an integrative perspective on amphiphilic cyclodextrins, the manuscript being divided into two parts, one devoted to the properties of amphiphilic cyclodextrins, while the second one is dedicated to their biomedical applications, with an emphasis on cancer therapy.