A comparison of pain tolerance during X-ray hysterosalpingography and sonohysterosalpingography. Albunex Study Group.

The objective of this study was to determine patient perception of the level of discomfort during sonohysterosalpingography (sono-HSG) compared with standard X-ray hysterosalpingography (HSG). This was a prospective, operator-blinded, multicenter study using both numerical ranking and a visual analog scale to quantify discomfort. Sono-HSG utilizing Albunex was associated with a significantly lower mean intensity of pain than the instillation of X-ray contrast media. Sono-HSG is an alternative to X-ray HSG in the evaluation of the uterus and fallopian tubes and compares favorably with respect to patient discomfort.