[The effect of x-ray contrast media on the blast transformation of human peripheral blood T-lymphocytes in vitro].

The effects of radiopaque agents on peripheral blood T-lymphocyte blast transformation were in vitro studied in healthy donors. It was shown that depending on the dose and type, radiopaque agents activated spontaneous proliferation of these cells and inhibited or activated PGA-induced proliferation. An individual sensitivity of peripheral blood lymphocytes to the radiopaque agents was revealed. There was a positive correlation between the functional response of peripheral blood lymphocytes to PGA and the degree of bilignost-induced inhibition of this reaction. There was also antagonism of some radiopaques in response to peripheral blood T-lymphocyte blast transformation.