JACC. Case reports · 2025
Autoimmune Reaction and the Management of Recurrent Bioprosthetic Pulmonary Valve Dysfunction.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Ezekwueme Francis E, Goldstein Bryan H, Bright Carley, Mathier Michael, DaSilva Luciana, Fajt Merritt L, Saraf Anita
Аннотация
BACKGROUND: Bioprosthetic valve failure is a significant and debilitating sequela in cardiac patients caused primarily by structural changes in valve leaflets due to endocarditis, calcification, and thrombosis.
CASE SUMMARY: We describe a rare case of bioprosthetic pulmonary valve failure due to an allergic reaction to molybdenum within the valve cage. We describe the clinical presentation, clinical methods leading to the diagnosis, and treatment progression until we could resolve symptoms and a significant return of valvular competency.
DISCUSSION: After excluding infectious etiologies as a cause, we used skin allergy testing to identify molybdenum as the allergic agent. The patient's symptoms and valve function improved and stabilized with immunosuppression and antihistamines.
TAKE-HOME MESSAGES: Allergy to a valve metal component was diagnosed with skin allergy and treated with immunosuppression and antihistamines.
CASE SUMMARY: We describe a rare case of bioprosthetic pulmonary valve failure due to an allergic reaction to molybdenum within the valve cage. We describe the clinical presentation, clinical methods leading to the diagnosis, and treatment progression until we could resolve symptoms and a significant return of valvular competency.
DISCUSSION: After excluding infectious etiologies as a cause, we used skin allergy testing to identify molybdenum as the allergic agent. The patient's symptoms and valve function improved and stabilized with immunosuppression and antihistamines.
TAKE-HOME MESSAGES: Allergy to a valve metal component was diagnosed with skin allergy and treated with immunosuppression and antihistamines.